| (Sainton's disease), a familial disease or congenital disorder characterized by failure to form, or retarded formation of, the clavicles; delayed closure of the sutures and fontanels; and delayed eruption of teeth, with formation of supernumerary teeth. Cleidocranial dysostosis is characterized by underdevelopment of the maxillae, agenesis or aplasia of the clavicle, abnormalities in other skeletal bones and muscles, and irregularities of the dentition. The syndrome may be mutational or transmitted on an autosomal dominant basis. |